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Importance of nitric oxide for local increases of blood flow in rat cerebellar cortex during electrical stimulation
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Add-on to metformin with or without SGLT2 inhibitor SURPASS-3 (NCT03882970) was a 52-week open-label trial that randomized 1444 adult patients with type 2 diabetes mellitus with inadequate glycemic control on stable doses of metformin with or without SGLT2 inhibitor to the addition of subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or insulin degludec 100 units/mL once daily
Given the implications of our study, further work in this area is likely to further illustrate the role of different parts of this system in maintaining a healthy balance between oxidative stress and antioxidants in neural tissue
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