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Moreover, TXNRD1 catalyzes the reduction of thioredoxin (TRX) to its dithiol-containing form and regulates cellular redox reactions for oxidative damage defense

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The gradual dose escalation strategy specifically aims to improve tolerability by allowing the digestive system to adjust to the medication's effects on gastric emptying and satiety signaling

Its copper delivery function is biologically significant because copper is a cofactor for lysyl oxidase (essential for collagen cross-linking), superoxide dismutase (antioxidant defense), and cytochrome c oxidase (mitochondrial energy production)