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34 A relative deficiency of anti-proteases, such as 1-antitrypsin, because of their inactivation by oxidants from cigarette smoke or released from inflammatory leucocytes, causes a protease/anti-protease imbalance in the lungs

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Intravenous (IV) Drips This is the most potent and rapid method

(2003) and Ozcan et al

It is possible that the effects are additive, that they are redundant, or that combining approaches produces unexpected outcomes

About 1.5% of the general population is estimated to have a deficiency of B12 but this figure increases sharply with age to about 6%