Thus, several microbiota-derived metabolites have been found to stimulate enteroendocrine L-cells producing GLP-1
The same receptor can also mobilize intracellular calcium and activate the ERK pathway, giving GLP-1 a signaling repertoire broader than cyclic AMP alone
It is a triple agonist that activates the glucose-dependent insulinotropic polypeptide (GIP), glucagon-like peptide-1 (GLP-1), and glucagon receptors
Belli, M
H.et al (2002)
Patients should be encouraged to consume a varied, nutrient-dense diet rich in: Iron found in red meat, poultry, fish, lentils, and fortified cereals Zinc present in shellfish, meat, seeds, and nuts Vitamin D obtained through sunlight exposure, oily fish, and fortified foods B vitamins , particularly B12 found in animal products and fortified alternatives For patients struggling to meet nutritional requirements through diet alone, a standard multivitamin supplement within recommended daily allowance (RDA) limits may be considered after discussion with a healthcare professional
