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Using gene-edited mice with humanised GLP-1 receptors, the team found that oral small-molecule GLP-1 drugs activated the central amygdala, a region associated with desire and reward that sits deeper in the brain than the hypothalamic and hindbrain networks where injectable peptide GLP-1s have been shown to act

Its usually recommended to have someone else perform the injection in this area, as it can be hard to see and reach properly on your own

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Therefore, clinicalTrials.gov

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