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Fasting in the context of CR is required for the benefits on insulin sensitivity, frailty, cognition, and lifespan in wild-type mice 12,54 , and indeed fasting alone without reduction of calories is sufficient for many of the molecular effects of CR as well as extending lifespan in wild-type mice 12,55
The patient was unaware of its presence
GLP-1 receptor agonism: A transformative approach for managing type-2 diabetes and obesity
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DOI: 10.1136/gpsych-2019-100056
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