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Koeth et al.: Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

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142 In addition, GLP-1 RA upregulated neurotrophic tyrosine kinase receptor type 2 and mTOR genes in the hippocampus of high-fat-fed mice, which are involved in regulating synaptic plasticity and LTP

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Furthermore, theres no evidence it works or is absorbed effectively when delivered through the skin