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Limitations of Use Hydrocodone bitartrate and acetaminophen tablets are contraindicated in patients with: Significant respiratory depression (see WARNINGS) Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment (see WARNINGS) Known or suspected gastrointestinal obstruction, including paralytic ileus (see WARNINGS) Hypersensitivity to hydrocodone or acetaminophen (e.g., anaphylaxis) (see WARNINGS and ADVERSE REACTIONS) Hydrocodone bitartrate and acetaminophen tablets contain hydrocodone, a Schedule II controlled substance

doi: 10.1111/1440-1681.12656 78 WangWGreenMChoiJEGijonMKennedyPDJohnsonJKet al

(7) Bartke A, Hascup E, Hascup K, Masternak MM